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Aknowledged on 2nd July 2020

Department of Nerosurgery

Department of Neurosurgery,Room No #580,
Max Super Speciality Hospital, Sector 1,
Vaishali, Ghaziabad, Uttar Pradesh 201012
Open now : Open 24 hours
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Gliomas

The most prevalent kind of brain tumors seen among adults are the gliomas. Among cancerous brain tumors, around 80% are gliomas. The supporting cells of the brain called glial cells are their source of development. The glial cells are further divided into three:

  • Astrocytes
  • Ependymal cells
  • Oligodendroglial cells
Glial tumors are are different types:
  • Astrocytomas: One of the most common that contribute to half of all the spinal cord and brain tumors. Astrocytes are the place where the glial cells develop. Astrocytes are the star-shaped glial cells which is a part of the supportive tissues of the brain. Even though they may occur at any part of the brain, the most common area is the neo cortex or cerebrum. Astrocytomas may affect people of any age and are most common among adults. Particularly, it affects middle-aged men. Astrocytes that are seen in the Posterior fossa (lower part) of the brain are more common among younger people and in children.
  • Ependymomas: They are derived from a neoplastic transformation of the ependymal cells lining the ventricular system. Two or three percentage of brain tumors constitute ependymomas. Most of them can be completely cured with appropriate treatment and some are not.
  • Glioblastoma multiforme(GBM): It is one of the most invasive kind of glial tumors. They may grow rapidly and affect the other tissues also. These kinds of tumors said to have a poor prognosis. They are most common among people between the age of 50 to 70 and especially seen more in women.
  • Medulloblastomas: They usually develop in the cerebellum. Medulloblastomas are usually seen among children. They are considered to be high-grade tumors, which are responsive to chemotherapy and radiation.
  • Oligodendrogliomas: They are derived from the brain and known as ‘the scavengers of brain’.

Treatments :

•             Surgery :  In Gliomas, Surgery to remove as much of the tumor as possible is usually the first step in treating most types of gliomas. Some times, gliomas are small and easy to separate from surrounding healthy brain tissue which makes complete surgical removal possible. In another cases, tumorscan not be separated from surrounding tissue or they're located near sensitive part in your brain and make surgery risky. In such situations your doctor removes as much of the tumor as is safe.

•             Radiation therapy : Radiation therapy mainly follows surgery in treatment of glioma, mainly high-grade gliomas. Radiation uses high-energy beams likes X-rays or protons to kill tumor cells. Radiation therapy for glioma comes from a machine outside our body (external beam radiation).

•             Chemotherapy : Chemotherapy uses drugs to kill tumor cells. Chemotherapy drugs may be taken in pill form (orally) or injected into a vein (intravenously). Chemotherapy are usually used in combination with radiation therapy to treat gliomas. chemotherapy drug normally used to treat gliomas is temozolomide (Temodar) is taken as a pill.


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